5/16/2025
Last update
5/16/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 31 g (About 1 Scoop)
Amount Per Serving
%DV
Calories
120
Total Fat
1.5 g
2%
Saturated Fat
1 g
5%
Cholesterol
60 mg
20%
Sodium
130 mg
6%
Total Carbohydrate
3 g
1%
Total Sugars
2 g
Protein
24 g
48%
Calcium
140 mg
10%
Potassium
150 mg
4%
Top Medical Research Studies
8
Riluzole effectively reduces bone pain
We explored whether riluzole could help ease bone pain caused by prostate cancer. Using a mouse model that mimicked human bone cancer pain, we treated some mice with riluzole while others were not.
Our findings indicated that riluzole significantly reduced pain sensitivity without hindering cancer progression or bone health. This treatment seems effective in offering relief from unpleasant pain sensations associated with bone metastases.
Our findings indicated that riluzole significantly reduced pain sensitivity without hindering cancer progression or bone health. This treatment seems effective in offering relief from unpleasant pain sensations associated with bone metastases.
Read More
8
We explored a unique case where a 39-year-old man presented with severe bone pain due to Sjögren's syndrome-related renal issues. He also exhibited symptoms like polydipsia and hypophosphatemic osteomalacia. After one month of potassium, phosphate, vitamin D, and sodium bicarbonate supplements, we observed significant relief in his bone pain, alongside normalized potassium and phosphorus levels. This indicates that potassium intake can play a crucial role in alleviating bone pain linked to kidney dysfunction in autoimmune conditions, such as Sjögren's syndrome.
Read More
7
We explored a unique case of a 22-year-old woman with Sjögren’s syndrome who experienced unexpected symptoms, including severe bone pain and hypokalemic paralysis.
After thorough diagnostics, including serological tests and assessments, she was diagnosed with distal renal tubular acidosis linked to her condition.
An intensive treatment plan focused on stabilizing her potassium levels effectively relieved her symptoms within just two weeks.
This case highlights the importance of recognizing Sjögren's syndrome early, especially in younger patients, and the need for a comprehensive approach to treatment.
After thorough diagnostics, including serological tests and assessments, she was diagnosed with distal renal tubular acidosis linked to her condition.
An intensive treatment plan focused on stabilizing her potassium levels effectively relieved her symptoms within just two weeks.
This case highlights the importance of recognizing Sjögren's syndrome early, especially in younger patients, and the need for a comprehensive approach to treatment.
Read More
Most Useful Reviews
9
Effective pain relief
It does the job! Since starting at the gym last year, I endured days of bone pain afterwards. This powder (currently on my second container) significantly dulls the pain when taken after workouts. Thanks to this product, I can exercise much more frequently. I initially thought eating more meat would help, but this powder truly addresses my bone pain!
Read More
9
Amazing improvement
Excellent! The quality of this product is outstanding, with well-chosen ingredients. I appreciate the taste, health benefits, and effective packaging. My knee’s bone pain has vanished, thanks to collagen, which I believe is essential at any age. The improvement was noticeable after just a short course of use.
Read More
7.5
Quick recovery
Easy to drink! It tastes better than I expected and dissolves well. Mixing it with water gives a strawberry milk-like flavour. After muscle training, drinking it on the same day quickly alleviates any bone pain the next day. I’m excited to try various flavours next time.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.6
- All Researches
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
8
Riluzole effectively reduces bone pain
We explored whether riluzole could help ease bone pain caused by prostate cancer. Using a mouse model that mimicked human bone cancer pain, we treated some mice with riluzole while others were not.
Our findings indicated that riluzole significantly reduced pain sensitivity without hindering cancer progression or bone health. This treatment seems effective in offering relief from unpleasant pain sensations associated with bone metastases.
Our findings indicated that riluzole significantly reduced pain sensitivity without hindering cancer progression or bone health. This treatment seems effective in offering relief from unpleasant pain sensations associated with bone metastases.
Read More
8
We explored a unique case where a 39-year-old man presented with severe bone pain due to Sjögren's syndrome-related renal issues. He also exhibited symptoms like polydipsia and hypophosphatemic osteomalacia. After one month of potassium, phosphate, vitamin D, and sodium bicarbonate supplements, we observed significant relief in his bone pain, alongside normalized potassium and phosphorus levels. This indicates that potassium intake can play a crucial role in alleviating bone pain linked to kidney dysfunction in autoimmune conditions, such as Sjögren's syndrome.
Read More
8
We examined the effects of low-dose adefovir therapy on bone pain in patients showing signs of nephrogenic hypophosphatemic osteomalacia. Over two years, five patients developed reduced phosphate levels and renal issues, leading to bone pain. After stopping the treatment and providing phosphate and potassium supplements, we noticed significant decreases in bone pain and improved mobility in some patients. This indicates that potassium treatment, alongside phosphate supplementation, can positively affect bone pain related to kidney issues stemming from adefovir.
Read More
7
We explored a unique case of a 22-year-old woman with Sjögren’s syndrome who experienced unexpected symptoms, including severe bone pain and hypokalemic paralysis.
After thorough diagnostics, including serological tests and assessments, she was diagnosed with distal renal tubular acidosis linked to her condition.
An intensive treatment plan focused on stabilizing her potassium levels effectively relieved her symptoms within just two weeks.
This case highlights the importance of recognizing Sjögren's syndrome early, especially in younger patients, and the need for a comprehensive approach to treatment.
After thorough diagnostics, including serological tests and assessments, she was diagnosed with distal renal tubular acidosis linked to her condition.
An intensive treatment plan focused on stabilizing her potassium levels effectively relieved her symptoms within just two weeks.
This case highlights the importance of recognizing Sjögren's syndrome early, especially in younger patients, and the need for a comprehensive approach to treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective pain relief
It does the job! Since starting at the gym last year, I endured days of bone pain afterwards. This powder (currently on my second container) significantly dulls the pain when taken after workouts. Thanks to this product, I can exercise much more frequently. I initially thought eating more meat would help, but this powder truly addresses my bone pain!
Read More
9
Amazing improvement
Excellent! The quality of this product is outstanding, with well-chosen ingredients. I appreciate the taste, health benefits, and effective packaging. My knee’s bone pain has vanished, thanks to collagen, which I believe is essential at any age. The improvement was noticeable after just a short course of use.
Read More
7.5
Quick recovery
Easy to drink! It tastes better than I expected and dissolves well. Mixing it with water gives a strawberry milk-like flavour. After muscle training, drinking it on the same day quickly alleviates any bone pain the next day. I’m excited to try various flavours next time.
Read More
6
Less muscle discomfort
1 people found this helpful
The taste varies for people. I give it to my children after evening practice. They find it easy to consume with milk. I’ve noticed less muscle pain, and sometimes I take it after their exercise. They enjoy it, although it might not suit everyone's taste, but it does help with bone pain.
Read More
Frequently Asked Questions
9
Effective pain relief
It does the job! Since starting at the gym last year, I endured days of bone pain afterwards. This powder (currently on my second container) significantly dulls the pain when taken after workouts. Thanks to this product, I can exercise much more frequently. I initially thought eating more meat would help, but this powder truly addresses my bone pain!
9
Amazing improvement
Excellent! The quality of this product is outstanding, with well-chosen ingredients. I appreciate the taste, health benefits, and effective packaging. My knee’s bone pain has vanished, thanks to collagen, which I believe is essential at any age. The improvement was noticeable after just a short course of use.
7.5
Quick recovery
Easy to drink! It tastes better than I expected and dissolves well. Mixing it with water gives a strawberry milk-like flavour. After muscle training, drinking it on the same day quickly alleviates any bone pain the next day. I’m excited to try various flavours next time.
6
Less muscle discomfort
1 people found this helpful
The taste varies for people. I give it to my children after evening practice. They find it easy to consume with milk. I’ve noticed less muscle pain, and sometimes I take it after their exercise. They enjoy it, although it might not suit everyone's taste, but it does help with bone pain.
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
8
We explored a unique case where a 39-year-old man presented with severe bone pain due to Sjögren's syndrome-related renal issues. He also exhibited symptoms like polydipsia and hypophosphatemic osteomalacia. After one month of potassium, phosphate, vitamin D, and sodium bicarbonate supplements, we observed significant relief in his bone pain, alongside normalized potassium and phosphorus levels. This indicates that potassium intake can play a crucial role in alleviating bone pain linked to kidney dysfunction in autoimmune conditions, such as Sjögren's syndrome.
8
We examined the effects of low-dose adefovir therapy on bone pain in patients showing signs of nephrogenic hypophosphatemic osteomalacia. Over two years, five patients developed reduced phosphate levels and renal issues, leading to bone pain. After stopping the treatment and providing phosphate and potassium supplements, we noticed significant decreases in bone pain and improved mobility in some patients. This indicates that potassium treatment, alongside phosphate supplementation, can positively affect bone pain related to kidney issues stemming from adefovir.
References
- von Brackel FN, Grambeck J, Barvencik F, Amling M, Oheim R. In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution. JBMR Plus. 2024;8:ziae139. 10.1093/jbmrpl/ziae139
- Chen R, Fang L, Fang X, Ning J. Sjögren's syndrome complicated with hypothyroidism and osteomalacia: A case report. Medicine (Baltimore). 2024;103:e39771. 10.1097/MD.0000000000039771
- Delanne-Cuménal M, Lamoine S, Meleine M, Aissouni Y, Prival L, et al. The TREK-1 potassium channel is involved in both the analgesic and anti-proliferative effects of riluzole in bone cancer pain. Biomed Pharmacother. 2024;176:116887. 10.1016/j.biopha.2024.116887
- Filler G, Schott C, Salerno FR, Ens A, McIntyre CW, et al. Growth hormone therapy in HHRH. Bone Rep. 2022;16:101591. 10.1016/j.bonr.2022.101591
- Geng Y, Zhao Y, Zhang Z. Tubulointerstitial nephritis-induced hypophosphatemic osteomalacia in Sjögren's syndrome: a case report and review of the literature. Clin Rheumatol. 2018;37:257. 10.1007/s10067-017-3762-y
- Xu Y, Shen P, Pan X, Chen N. Nephrogenic hypophosphatemic osteomalacia during adefovir monotherapy for chronic hepatitis B monoinfection. Clin Kidney J. 2013;6:379. 10.1093/ckj/sft069
- Earle KE, Seneviratne T, Shaker J, Shoback D. Fanconi's syndrome in HIV+ adults: report of three cases and literature review. J Bone Miner Res. 2004;19:714.
